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Dr. Trichur R Raju

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Dr. Trichur R Raju

Faculty Profile

Designation
Professor and HOD
Associated with NIMHANS as faculty since (Month and Year)
Tuesday, August 1, 1989
Educational Qualifications
M.Sc. (Faculty of Medicine), Ph.D. ( Australian National University)
Awards, Fellowships and Recognitions, Memberships
  • Government of India Merit Scholarship holder (1971-1974).
  • First class, First in M.Sc. Physiology of the University of Madras (1974).
  • Felicitated by the Association of Physiologists and Pharmacologists of India for being the best M.Sc. candidate for the year 1974.
  • Australian National University Research Scholarship award (1975-1979).
  • Harvard University – NIH Fellowship award (1979-1982).
  • One of the leading investigators of a team lead by Prof. M.R. Bennett of the Sydney University, which was awarded the highest grant ever given to bio-medical research in Australia at that time (1981-87).
  • Invited Lecturer and Chairman of National as well as International Scientific meetings/symposia/workshops.
  • Serving as a referee for National and International Journals including “Science”, Experimental Neurology, Molecular Neuroscience, Indian Journal of Medical Research, Indian Journal of Experimental Biology, Indian Journal of Physiology and Pharmacology.
  • R.C.Shukla Oration at King George’s Medical College, Lucknow (2000).
  • General Secretary and Chief Executive of Association of Physiologists and Pharmacologists of India (1998-2001)
  • Awarded Prof. Baldev Singh Oration for Outstanding contributions in Neuroscience from the Association of Physiologists and Pharmacologists of India (APPI), India (2002).
  • Fr Balam Memorial Oration from St. Joseph’s College, Tiruchirapalli, India (2004).
  • Elected as Fellow of National Science Academy (FASc) (2005).
  • Dean of Faculty of NIMHANS (2004-6 and 2009-11)
  • Invited Speaker, Inaugural Symposium on Brain and mind Research in the Asia Pacific Region, Sydney, Austalia (2006)
  • Prof. A. K. Mukherjee Memorial Oration of the Physiological Society of India (2008).
  • Invited Speaker, Third Symposium on Brain and mind Research in the Asia Pacific Region, Seoul, South Korea (2010)
  • Major Gen S.L. Bhatia Oration Award by the Association of Physiologists and Pharmacologists of India (2011).
  • Elected Fellow of the Indian Academy of Neuroscience (2012)
  • President, Bangalore Chapter of Society for Neuroscience (2008-till date)
  • President, Bangalore Chapter of Society for Neuroscience (2008-till date)
  • Expert Member , Law Commission of India (2014).
Contact Information
Phone : +91-080-26995168 (O) Email: trraju@nimhans.kar.nic.in, trraju.nimhans@gmail.com
Areas of Research Interest
  • Pathophysiology of Amyotrophic Lateral Sclerosis
  • Trophic factors in Development and Neuroprotection
  • CNS regeneration and role of resident stem cells
  • Stem Cell derived models for human Neurological diseases
  • Neuronal plasticity

Research

Status: Ongoing

    Title:
    Directed differentiation of Human Embryonic Stem Cells into Motor neurons, their characterization and use as a cellular model for Sporadic Amyotrophic Lateral Sclerosis
    Status:
    Ongoing
    Project Start/Completion Date:
    01-Nov-2011 to 31-Oct-2016
    Staff:
    Dr. Trichur R Raju
    Funding Agency:
     
    Research Papers:
     
    Principal Investigator:
    Dr. Trichur R Raju
    Other Investigators:
    1. Name: 
      Dr. T N Sathyaprabha
      Role: 
      Co-Investigator
    2. Name: 
      Dr. A Nalini
      Role: 
      Co-Investigator

     
    Summary:

    The objective of this study is to differentiate the Human Embryonic Stem Cells BJNhem19/ BJNhem20 into motor neurons & to characterize them. The effect of ALS-CSF on these motor neurons will be more

    Title:
    Translational Research in Amyotrophic Lateral Sclerosis (ALS) – Development of Biomarkers for diagnosis, monitoring disease progression and evaluation of toxicity
    Status:
    Ongoing
    Project Start/Completion Date:
    01-Mar-2014 to 28-Feb-2019
    Staff:
    Dr. Trichur R Raju
    Funding Agency:
    ICMR
    Research Papers:
     
    Principal Investigator:
    Dr. Trichur R Raju
    Other Investigators:
    1. Name: 
      Dr. A Nalini
      Role: 
      Co-Investigator
    2. Name: 
      Dr. T N Sathyaprabha
      Role: 
      Co-Investigator
    3. Name: 
      Dr. Phalguni Anand Alladi
      Role: 
      Co-Investigator

     
    Summary:

    This study aims at identifying and validating functional application of biomarkers in diagnosis of the fatal neurodegenerative disease Amyotrophic lateral Sclerosis, for which no cure is hitherto known other than the limited use of the anti-inflammatory marker Riluzole

    Accordingly, the more

    Title:
    Glial Responses in Sporadic Amyotrophic Lateral Sclerosis
    Status:
    Ongoing
    Project Start/Completion Date:
    01-Jul-2012 to 30-Jun-2015
    Staff:
    Dr. Trichur R Raju
    Funding Agency:
    DBT
    Research Papers:
     
    Principal Investigator:
    Dr. Trichur R Raju
    Other Investigators:
    1. Name: 
      Dr. Phalguni Anand Alladi
      Role: 
      Co-Investigator
    2. Name: 
      Dr. T N Sathyaprabha
      Role: 
      Co-Investigator
    3. Name: 
      Dr. A Nalini
      Role: 
      Co-Investigator

     
    Summary:

    Glial cells play a crucial role in the normal functioning of the CNS, as well as pathological conditions like neurodegeneration. In Amyotrophic lateral sclerosis (ALS) too, the protective as well as more

Status: Completed

    Title:
    Isolation and characterization of toxic factor(s) present in CSF of patients suffering from Amyotrophic Lateral Sclerosis
    Status:
    Completed
    Project Start/Completion Date:
    01-Dec-2012 to 01-Nov-2017
    Staff:
    Dr. Trichur R Raju
    Funding Agency:
    DBT
    Research Papers:
     
    Principal Investigator:
    Dr. Trichur R Raju
    Other Investigators:
    1. Name: 
      Dr. T N Sathyaprabha
      Role: 
      Co-Investigator
    2. Name: 
      Dr. A Nalini
      Role: 
      Co-Investigator
    3. Name: 
      Dr. Phalguni Anand Alladi
      Role: 
      Co-Investigator

     
    Summary:

    The project aimed at identifying the toxic factor(s) present in CSF of ALS patients. Quantitative proteomic analysis of ALS – CSF samples compared to normal CSF samples identified 819 more